Hyaluronate lyase used for promoting penetration in topical agents

US6719986B1 · kind B1 · utility

Assignee

• Esparma GmbH · DE

Inventors

• Wolfgang Wohlrab · Bodenwerder, DE
• Reinhard Neubert · Bodenwerder, DE
• Christoph Huschka · Bodenwerder, DE
• Peter-Jürgen Müller · Jena, DE
• Jörg-Herman Ozegowski · Jena, DE
• Dieter Koegst · Osterweddingen, DE
• Gerhard Fries · Gommern, DE

Key dates

• Filing date: Sep 5, 2001
• Grant date: Apr 13, 2004
• Expiry date: Sep 5, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2800/70
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to an agent for treating skin diseases and/or functional disorders of the skin on the basis of different medicaments and/or auxiliary substances through promotion of penetration from topical formulations into the skin. According to the invention, the agent is composed of a hyaluronate lyase produced by microbial means and a medicament, preferably a hydrophilic medicament and/or auxiliary substances in different galenic formulations including colloidal carrier systems. The areas of application for the invention in human and veterinary medicament relate to the treatment, prophylaxis and/or metaphylaxis of skin diseases, functional disorders of the skin, the processes of skin ageing and dry skin conditions.