Method for preparation of the supersaturated solution of calcium phosphate and the thin film of calcium phosphate crystal by using the solution
US6720023B1 · kind B1 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 2, 2001 |
| Grant date | Apr 13, 2004 |
| Priority date | — |
| Expiry date | Mar 2, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC01B25/32
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates to a method for preparation of the supersaturated calcium and phosphate ions solution and a method for preparation of the thin film of calcium phosphate crystal on solid surface by using the said solution. Particularly, the lowered temperature and/or the use of suitable buffer system inhibit the nucleation of calcium phosphate in aqueous solution, and thereby highly supersaturated calcium and phosphate ions solution can be prepared. And the thin film of calcium phosphate crystal on solid surface can be prepared with rapidity and good quality of high reactivity and low crystallinity by using the said solution. Also the thin film of calcium phosphate crystal prepared according to the present invention has biocompatibility and can be applied as biomaterials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.