Patent · US Expired

Membrane and electrode structure for implantable sensor

US6721587B2 · kind B2 · utility

508Cited by
5References
22Claims
0Family size

Assignee

Inventor

Key dates

Filing dateFeb 15, 2002
Grant dateApr 13, 2004
Priority date
Expiry dateFeb 15, 2022

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61B5/14532
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

The invention is the design of a biological measuring device for the determination of the concentration of biomolecules (e.g. glucose) in an environment which is designed for implantation into an individual or for use in the context of an external apparatus. The device contains a composite membrane that is essentially entirely permeable to oxygen and permeable to larger biomolecules only in discrete hydrophilic regions. The membrane diffusionally limits the access of biomolecules to an enzyme, present in the hydrophilic region that catalyzes the oxidation of the biomolecule to produce hydrogen peroxide. A sensor in communication with the hydrophilic region is used to determine the amount of product produced or the amount of excess oxygen present allowing for the concentration of the biomolecule to be determined.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.