Chk1 and uses thereof
US6723498B1 · kind B1 · utility
11Cited by
0References
38Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 30, 1999 |
| Grant date | Apr 20, 2004 |
| Priority date | — |
| Expiry date | Jun 30, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/9121
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Increased expression of Chk1 is associated with drug resistance of certain cells (e.g., cancer cells). The invention provides methods for identifying drug resistant cells by measuring the expression or activity of Chk1, methods for identifying modulators of drug resistance, and methods for modulating drug resistance by modulating the expression or activity of Chk1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.