Patent · US Expired

Multi-sample fermentor and method of using same

US6723555B2 · kind B2 · utility

2Cited by
25References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 8, 2002
Grant dateApr 20, 2004
Priority date
Expiry dateFeb 8, 2022

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/818
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A fermentation apparatus is constructed to produce a known and repeatable amount of untainted fermentation product using multiple fermentation vessels. To facilitate further processing compatible with other product processing steps, the fermentation apparatus has an array of sample vessels arranged in a container frame. The container frame is configured to hold the sample vessels during fermentation and to transport the vessel array to or from another processing station. Corresponding to the number of sample vessels in the sample vessel array, a cannula array is configured such that each cannula may be placed inside a sample vessel. The cannula array is attached to a gas distributor that delivers oxygen and/or one or more other gases from a gas source through the cannula into the sample vessel. Because the fermentation volume for each individual sample vessel is smaller than a bulk fermentation apparatus, the fermentation product yields are predictable and cell growth rates can be effectively optimized.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.