Methods and compositions for the treatment of motor neuron injury and neuropathy
US6723698B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 25, 1997 |
| Grant date | Apr 20, 2004 |
| Priority date | — |
| Expiry date | Sep 25, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are therapeutic treatment methods, compositions and devices for maintaining neural pathways in a mammal, including enhancing survival of neurons at risk of dying, inducing cellular repair of damaged neurons and neural pathways, and stimulating neurons to maintain their differentiated phenotype. In one embodiment, the invention provides means for stimulating CAM expression in neurons. The invention also provides means for evaluating the status of nerve tissue, including means for detecting and monitoring neuropathies in a mammal. The methods, devices and compositions include a morphogen or morphogen-stimulating agent provided to the mammal in a therapeutically effective concentration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.