Protein analogs of brain-derived neurotrophic factor
US6723701B2 · kind B2 · utility
6Cited by
3References
7Claims
0Family size
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Key dates
| Filing date | Dec 19, 2000 |
| Grant date | Apr 20, 2004 |
| Priority date | — |
| Expiry date | Dec 19, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The in vivo circulating life and/or absorption of cationic therapeutic proteins, including but not limited to basic proteins such as NT-3 and BDNF, can be increased by generating analogs that have a lower isoelectric point and, preferably, also a lower protein charge relative to the protein of native sequence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.