Patent · US Expired

Heterocyclic derivatives as inhibitors of factor Xa

US6723723B1 · kind B1 · utility

0Cited by
42References
13Claims
0Family size

Assignee

Inventor

Key dates

Filing dateNov 15, 2001
Grant dateApr 20, 2004
Priority date
Expiry dateNov 15, 2021

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/28
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to heterocyclic derivatives, or pharmaceutically-acceptable salts thereof, of formula (I) wherein: A is an optionally substituted 5- or 6-membered monocyclic aromatic ring containing 1, 2 or 3 ring heteroatoms selected from oxygen, nitrogen and sulphur atoms; which possess antithrombotic and anticoagulant properties and are accordingly useful in methods of treatment of humans or animals. The invention also relates to processes for the preparation of the heterocyclic derivatives, to phaautical compositions containing them and to their use in the manufacture of medicaments for use in the production of an antithrombotic or anticoagulant effect.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.