Dimethylformamide synthesis via reactive distillation of methyl formate and dimethylamine
US6723877B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 16, 2003 |
| Grant date | Apr 20, 2004 |
| Priority date | — |
| Expiry date | Jun 16, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A continuous process for the production of dimethylformamide comprising the steps:(a) reacting methyl formate and dimethylamine in a reactive distillation column under conditions to form dimethylformamide and by-product methanol;(b) vaporizing the by-product methanol and generating a liquid dimethylformamide while in said reactive distillation column;(c) removing at least a major portion of the by-product methanol as an overhead from said reactive distillation column;(d) removing a crude liquid dimethylformamide containing residual by-product methanol as a bottoms fraction from said reactive distillation column;(e) introducing said bottoms fraction containing dimethylformamide and residual by-product methanol to a purification column wherein the by-product methanol is removed from said dimethylformamide as an overhead and purified dimethylformamide is removed as a bottoms fraction; and, optionally,(f) recycling the by-product methanol removed as an overhead from the purification column to the reactive distillation column.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.