Intergrase assay
US6727058B2 · kind B2 · utility
14Cited by
12References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 12, 2001 |
| Grant date | Apr 27, 2004 |
| Priority date | — |
| Expiry date | Jun 10, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/20222
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides packaging cell lines and recombinant lentiviral or retroviral particles produced therefrom, particularly pseudotyped retroviral particles. The packaging cell lines of the invention are produced by inducibly expressing an envelope protein by methods described herein. Also described is a screening assay for compounds that affect integration of viral nucleic acid into target (e.g., host) nucleic acid. Such compounds are identified based on their effect on viral integrase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.