Assays and reagents for identifying anti-fungal agents, and uses related thereto
US6727082B1 · kind B1 · utility
0Cited by
16References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 13, 1998 |
| Grant date | Apr 27, 2004 |
| Priority date | — |
| Expiry date | Mar 13, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/91165
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to rapid, reliable and effective assays for screening and identifying pharmaceutically effective compounds that specifically inhibit the biological activity of fungal GTPase proteins, particularly GTPases involved in cell wall integrity, hyphael formation, and/or other cellular functions critical to pathogenesis. Another aspect of the present invention relates to novel Candida genes and gene products.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.