Patent · US Expired

Assays, antibodies, and standards for detection of oxidized and MDA-modified low density lipoproteins

US6727102B1 · kind B1 · utility

21Cited by

16References

19Claims

0Family size

Assignee

Leuven Research & Development VZW · BE

Inventors

Paul Holvoet · Kessel-Lo, BE
Desire Collen · Winksele, BE

Key dates

Filing date	Dec 20, 1999
Grant date	Apr 27, 2004
Priority date	—
Expiry date	Dec 20, 2019

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/104165
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Immunoassays for malondialdehyde-modified low density lipprotein (MDA-modified LDL) and oxidized low density lipprotein (OxLDL), monoclonal antibodies (and the cell lines for them) for use in the assays, and a storage-stable standard (which may be used as a calibrator and/or control) are disclosed. MDA-modified LDL and OxLDL are implicated in atherosclerosis and its etiology.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.