Heteroaryl tropane derivatives as superior ligands for nociceptin receptor ORL-1
US6727254B2 · kind B2 · utility
5Cited by
4References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 6, 2002 |
| Grant date | Apr 27, 2004 |
| Priority date | — |
| Expiry date | Nov 6, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel compounds of the formula whereinR is optionally substituted heteroaryl or R1 is H or C1-C6 alkyl; andR2 and R3 are —CH3, —OCH3 or halo;or a pharmaceutically acceptable salt or solvate thereof, pharmaceutical compositions therefore, and the use of said compounds in the treatment of pain, anxiety, cough, asthma, depression and alcohol abuse are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.