Dihydrothiaphenanthrenecarbonylguanidines: composition, process of making, and use as medicament or diagnostic aid

US6730697B2 · kind B2 · utility

Assignee

• Aventis Pharma Deutschland GmbH · DE

Inventors

• Heinz-Werner Kleemann · Bischofsheim, DE
• Peter Below · Frankfurt, DE

Key dates

• Filing date: Jan 23, 2003
• Grant date: May 4, 2004
• Expiry date: Jan 23, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D335/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Dihydrothiaphenanthrenecarbonylguanidine compound of formula I These compounds are potentially suitable as antiarrythmic medicaments with a cardioprotective component for prophylaxis of an infarction and treatment of infarction, and for treatment of angina pectoris. They may also inhibit in a preventive manner the pathophysiological processes involved in the development of ischemia-induced damage, especially in the initiation of ischemia-induced cardiac arrhythmias.