Purification of plasmid DNA of pharmaceutical quality
US6730781B1 · kind B1 · utility
3Cited by
2References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 15, 1998 |
| Grant date | May 4, 2004 |
| Priority date | — |
| Expiry date | May 10, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6806
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention is directed to a process for purifying double-stranded DNA, comprising using ceramic hydroxyapatite column chromatography. The invention is also directed to a purified recombinant plasmid DNA composition, comprising a chromosomal DNA content that is less than or equal to 0.01% as well as to a composition comprising DNA prepared by the foregoing process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.