Process for the preparation of substituted octanoyl amides
US6730798B2 · kind B2 · utility
4Cited by
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10Claims
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Key dates
| Filing date | Jan 3, 2003 |
| Grant date | May 4, 2004 |
| Priority date | — |
| Expiry date | Jan 18, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/33
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula (II) are simultaneously halogenated in the 5 position and hydroxylated in the 4 position under lactonization, the halolactone is converted into a hydroxylactone and then the hydroxy group into a leaving group, the leaving group is replaced with azide, the lactone amidated and then the azide converted to the amine group, in order to obtain compounds of formula (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.