Agent and method for modulation of cell migration
US6730820B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | May 28, 1999 |
| Grant date | May 4, 2004 |
| Priority date | — |
| Expiry date | May 28, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/20
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A GON-1 migration protein in C. elegans and a gon-1 gene encoding same are disclosed. The protein, termed GON-1, shows structural similarity to a protein produced by an up-regulated RNA in an advanced tumor cell. Although the tumor cell protein has not previously been identified as having any role in cell migration, it is disclosed herein that the related GON-1 protein is required for cell migration and is involved in shaping tissues or organs. It is deduced that the protein is also a target for modulators of cell migration and tissue shaping.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.