Patent · US Expired

Methods for encapsulating nucleic acids in lipid bilayers

US6734171B1 · kind B1 · utility

43Cited by
38References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 9, 1998
Grant dateMay 11, 2004
Priority date
Expiry dateOct 9, 2018

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K48/0025
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to lipid-based formulations for nucleic acid delivery to cells, methods for the preparation of such formulations and, in particular, to lipid encapsulated plasmids. The compositions are safe and practical for clinical use. In addition, the present invention provides methods for introducing nucleic acids into cells and for inhibiting tumor growth in cells using such lipid-nucleic acid formulations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.