Tissue-engineered ligament
US6737053B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 10, 2000 |
| Grant date | May 18, 2004 |
| Priority date | — |
| Expiry date | Nov 10, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2/08
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An apparatus and method for the reconstruction of a previously torn ligament using a tissue-engineered ligament. The tissue-engineered ligament includes a scaffold of biocompatible material having at least one layer and forming a sheet. The scaffold is placed in a cultured medium for seeding with fibrocyte forming cells. The seeded scaffold is then placed in an incubator to increase the number of cells. The seeded scaffold is then formed into a slender structure suitable for implantation. The method of making a tissue-engineered ligament includes forming a scaffold of biocompatible material having at least one layer forming a sheet. Next, the scaffold sheet is seeded with fibrocyte forming cells. The method further includes increasing the number of cells on the seeded scaffold and forming a slender structure suitable for implantation from the scaffold.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.