Sequences encoding PhzO and methods

US6737260B1 · kind B1 · utility

Assignees

• The United States of America, as represented by the Secretary of Agriculture · US
• Washington State University Research Foundation · US

Inventors

• Linda S. Thomashow · Pullman, US
• Shannon M. Delaney · Schiller Park, US
• Dmitri V. Mavrodi · Hattiesburg, US
• David M. Weller · Pullman, US

Key dates

• Filing date: Sep 27, 2001
• Grant date: May 18, 2004
• Expiry date: Feb 20, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N9/0004
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention is directed to nucleic acid sequences which encode polypeptides having PhzO activity, namely, the ability to convert phenazine-1-carboxylic acid to a 2-hydroxylated phenazine, and isolated polypeptides having this activity. The invention is also directed to recombinant nucleic acid molecules, vectors, and host cells including the nucleic acid sequences as well as methods for producing and using the polypeptides, including expression in bacterial or plant cells to inhibit fungal pathogens.