Patent · US Expired

Anti-bacterial agents based upon oxoanion binding

US6737415B2 · kind B2 · utility

3Cited by
4References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 22, 2002
Grant dateMay 18, 2004
Priority date—
Expiry dateAug 22, 2022

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of the structure I: are useful for treating bacterial growth, wherein E is selected from the group consisting of B, P, and S, T1, and T2 are each independently selected from the group consisting of O, NR, and CH2, where R=H or C1-C8 alkyl, or C1-C8 oxoalkyl, and L is selected from the group consisting of ethylene, propylene, and four to six-membered alicyclic and aromatic rings, provided that structure I does not include AI-2-borate. The compounds may be used to treat bacterial infections in human beings and to regulate biofilm formation. Pharmaceutical compositions comprising one or more such compounds are useful for treating bacterial infections in human beings.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.