Apparatus and method for rapid disruption of cells or viruses
US6739531B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Oct 4, 2001 |
| Grant date | May 25, 2004 |
| Priority date | — |
| Expiry date | Dec 13, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N1/066
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An apparatus for disrupting cells or viruses comprises a container having a chamber for holding the cells or viruses. The chamber is defined by at least one wall having an external surface for contacting a transducer device. The transducer device has a vibrating surface for contacting the wall and for vibrating at an operating frequency and amplitude sufficient to generate pressure waves or pressure pulses in the chamber. The transducer device is coupled to the wall with a preload force sufficient to create a stress within the wall. The natural frequency of the wall, when the wall is stressed by the preload force, is equal to the operating frequency of the transducer device or differs from the operating frequency by less than 50% of the operating frequency.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.