Liposomal camptothecin formulations
US6740335B1 · kind B1 · utility
10Cited by
4References
80Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 24, 2000 |
| Grant date | May 25, 2004 |
| Priority date | — |
| Expiry date | Feb 24, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/496
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Liposomal encapsulated camptothecin formulations are provided. The liposomes have improved pharmacokinetics, enhanced efficacy as anti-tumor agents and provide an increased therapeutic index as compared to the free drug and topotecan. The formulations include liposomes comprising at least one phospholipid and a camptothecin or analog thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.