Adenoviral capsid containing chimeric protein IX
US6740525B2 · kind B2 · utility
19Cited by
1References
46Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 9, 2001 |
| Grant date | May 25, 2004 |
| Priority date | — |
| Expiry date | Aug 6, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a chimeric protein IX (pIX). The chimeric pIX protein has an adenoviral pIX domain and also a non-native amino acid. Where the non-native amino acid is a ligand that binds to a substrate present on the surface cells, the chimeric pIX can be used to target vectors containing such proteins to desired cell types. Thus, the invention provides vector systems including such chimeric pIX proteins as well as methods of infecting cells using such vector systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.