Electrophysiologic measure of endpoints for ablation lesions created in fibrillating substrates

US6743225B2 · kind B2 · utility

Assignee

• THE UAB RESEARCH FOUNDATION · US

Inventors

• Javier Sanchez · Homewood, US
• Jeffrey A. Hall · Birmingham, US
• Michael E. Benser · Valencia, US
• Raymond E. Ideker · Birmingham, US
• William M. Smith · Burlington, CA

Key dates

• Filing date: Mar 27, 2001
• Grant date: Jun 1, 2004
• Expiry date: Aug 10, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B2562/043
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Methods, systems, and computer program products measure electrical activity of the cardiac tissue proximate the lesion site during an ablation treatment, and then compare the measurements to determine whether the lesion is clinically efficacious so as to be able to block myocardial propagation. The methods can include obtaining the measurements and performing the ablation therapy while the subject is experiencing atrial fibrillation and may measure the standard deviation of the electrogram signal.