Prevention and treatment of amyloidogenic disease
US6743427B1 · kind B1 · utility
159Cited by
79References
19Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 28, 2000 |
| Grant date | Jun 1, 2004 |
| Priority date | — |
| Expiry date | Nov 28, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of A&bgr; in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the amyloid deposit. The methods are useful for prophylactic and therapeutic treatment of Alzheimer's disease. Preferred agents including N-terminal fragments of A&bgr; and antibodies binding to the same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.