Methods for differentiating and monitoring parathyroid and bone status related diseases
US6743590B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 26, 1999 |
| Grant date | Jun 1, 2004 |
| Priority date | — |
| Expiry date | Jun 26, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/811
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to novel methods and devices for differentiating in a patient parathyroid diseases, such as hyperparathyroidism and related bone diseases, from normal or non-disease states. One detects whole or non-fragmented (1 to 84) parathyroid hormone in a biological sample and also a large non-whole parathyroid hormone peptide fragment that can function as a parathyroid hormone antagonist. By either comparing values or using independently the value of either the large non-whole parathyroid hormone peptide fragment, the whole parathyroid hormone, or the combination of these values one is able to differentiate parathyroid and bone related disease states, as well as differentiate such states from normal states.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.