Method of cell culture using neurturin
US6743628B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 23, 1998 |
| Grant date | Jun 1, 2004 |
| Priority date | — |
| Expiry date | Dec 23, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel growth factor, neurturin, is disclosed. The human and mouse amino acid sequences have been identified. Human and mouse neurturin genomic DNA sequences have been cloned and sequences and the respective CDNA sequences identified. The subcloning into vectors and the preparation of cells stably transformed with the vectors is also disclosed. In addition, methods for treating degenerative conditions using neurturin, methods for detecting gene alterations and methods for detecting and monitoring patient levels of neurturin are provided. Methods for identifying additional members of the neurturin-GDNF family of growth factors are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.