Methods and compounds for inhibiting MRP1

US6743794B2 · kind B2 · utility

Assignee

• ELI LILLY AND COMPANY · US

Inventors

• Rosanne Bonjouklian · Indianapolis, US
• Jeffrey Daniel Cohen · Indianapolis, US
• Joseph Michael Gruber · Brownsburg, US
• Douglas Webb Johnson · Zionsville, US
• Louis Nickolaus Jungheim · Indianapolis, US
• Julian Stanley Kroin · Indianapolis, US
• Peter Ambrose Lander · Indianapolis, US
• Ho-Shen Lin · Indianapolis, US
• Mark Christopher Lohman · Boulder, US
• Brian S. Muehl · Indianapolis, US
• Bryan Hurst Norman · Indianapolis, US
• Vinod F. Patel · Acton, US
• Michael Enrico Richett · Indianapolis, US
• Kenneth Jeff Thrasher · Indianapolis, US
• Sreenivasarao Vepachedu · Vernon Hills, US
• Wesley Todd White · Indianapolis, US
• Yongping Xie · San Diego, US
• Jeremy Schulenburg York · Noblesville, US
• Brandon Parkhurst · Indianapolis, US
• Qiupang Wang · Hamden, US

Key dates

• Filing date: May 21, 2002
• Grant date: Jun 1, 2004
• Expiry date: May 21, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention further relates to a method of inhibiting MRP1 in a mammal which comprises administering to a mammal in need thereof an effective amount of a compound of formula (I).