Method of blood constituent monitoring using improved disposable extracorporeal conduit
US6746415B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | May 25, 2000 |
| Grant date | Jun 8, 2004 |
| Priority date | — |
| Expiry date | May 25, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M1/3624
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A cuvette having a pedestal for transmitting light through a relatively thin layer of blood. While the pedestal enables the use of a small path length it also permits the use of a high volume and/or high flow rate conduit. The pedestal further enables methods of determining various blood parameters in which the path length, d, is fixed; i.e., there are little or no pulsatile variations. Hence, the flow-through cuvette accommodates a large range of blood flow rates without any reduction in accuracy of the hematocrit measurement. The pedestal, because of its elliptical shape, does not damage or hemolyze the individual red blood cells as they pass through. A quantitative method for determining changes in blood volume in view of the path length is provided along with a method for measuring a patient's cardiac output and oxygen consumption rate. Cardiac output is obtained by injecting a saline arterial bolus and a saline venous bolus into a patient and measuring the change in hematocrit caused by each bolus. The oxygen consumption rate is then determined using the cardiac output and measuring the degree of oxygen saturation.Finally, an improved cuvette and corresponding method of measur…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.