Patent · US Expired

Heterocyclic compounds and their use as medicines

US6747024B1 · kind B1 · utility

6Cited by
1References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 30, 2002
Grant dateJun 8, 2004
Priority date
Expiry dateApr 30, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to new heterocyclic derivatives having an inhibitory activity on calpains and/or a trapping activity on reactive oxygen species, of formula in which A, X, Y, R1, R2 and Het represent variable groups.The invention also relates to their preparation methods, the pharmaceutical preparations containing them and their use for therapeutic purposes, in particular as inhibitors of calpains and/or traps of reactive oxygen species, selectively or non-selectively.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.