Methods of detecting protein arginine methyltransferase, and uses related thereto
US6747273B2 · kind B2 · utility
3Cited by
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7Claims
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Key dates
| Filing date | May 20, 2002 |
| Grant date | Jun 8, 2004 |
| Priority date | — |
| Expiry date | May 20, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to methods and reagents for detecting the presence of symmetrically and asymmetrically methylated arginine residues, either along or in polypeptides, using mass spectrometry. It also provides methods of determining structures of methylated arginine residues, methods of identifying substrates of PMRTs, and methods of conducting proteomic business using any of the suitable methods recited above.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.