Patent · US Expired

Micro-needles and methods of manufacture and use thereof

US6749792B2 · kind B2 · utility

185Cited by
14References
18Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJul 9, 2001
Grant dateJun 15, 2004
Priority date
Expiry dateJul 9, 2021

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61M2037/0053
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

A micro-needle is provided which is particularly useful for the minimally invasive sampling of a biological fluid and/or the minimally invasive delivery of a drug or other formulation across the skin. The micro-needle has a structure having a base at a proximal end and a vertex at a distal end, and an open lumen extending there through and through which fluid may be transferred. The structure defines a structural axis that intersects the lumenal axis defined by the open lumen. The point of intersection between these axes is at a point below the vertex of the micro-needle to provide a sharp apex at the distal end of the micro-needle and defines the general configuration of the distal end of the micro-needle, which may be selected or customized depending on the intended use of the microneedle. The micro-needle may be integral with a measurement device for measuring the concentration of a constituent within sampled biological fluid and/or with a fluid reservoir for containing a fluid to be delivered, and may also be used in conjunction with a remote control means. Methods of making and using the micro-needle of the present invention as well as kits comprising one or more of the micro-…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.