Methods for sterilizing preparations of digestive enzymes
US6749851B2 · kind B2 · utility
28Cited by
89References
53Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 31, 2001 |
| Grant date | Jun 15, 2004 |
| Priority date | — |
| Expiry date | Aug 31, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2/0029
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are disclosed for sterilizing preparations of digestive enzymes to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. These methods involve sterilizing preparations of digestive enzymes, such as trypsin, &agr;-galactosidase and iduronate-2-sulfatase, with irradiation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.