Methods and compositions for inhibition of membrane fusion-associated events, including HIV transmission
US6750008B1 · kind B1 · utility
7Cited by
5References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 9, 1999 |
| Grant date | Jun 15, 2004 |
| Priority date | — |
| Expiry date | Jul 9, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to peptides which exhibit potent anti-retroviral activity. The peptides of the invention comprise DP178 (SEQ ID:1) peptide corresponding to amino acids 638 to 673 of the HIV-1LAI gp41 protein, and fragments, analogs and homologs of DP178. The invention further relates to the uses of such peptides as inhibitory of human and non-human retroviral, especially HIV, transmission to uninfected cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.