Patent · US Expired

2-aminopyridine compounds and use thereof as drugs

US6750232B2 · kind B2 · utility

16Cited by
3References
39Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 23, 2003
Grant dateJun 15, 2004
Priority date
Expiry dateJan 23, 2023

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D409/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A class of substituted compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by formula (II), wherein R1 is selected from hydrido, halo, alkoxy, aryl, alkylthio, alkylamino, aralkoxy, azido and alkenyloxy; wherein R2 is selected from hydrido, cyano, hydroxyalkyl, haloalkyl, aminoalkyl, alkylaminoalkyl, alkylcarbonyloxyalkyl, aminocarbonyl and alkylcarbonylaminoalkyl; and wherein R5 and R6 are one more radicals independently selected from halo, alkylsulfonyl, aminosulfonyl, alkoxy and alkylthio; provided one of R5 and R6 is substituted with alkysulfonyl, aminosulfonyl, or haloalkylsulfonyl; or a pharmaceutically-acceptable salt thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.