SPR sensor system

US6752963B2 · kind B2 · utility

Assignee

• Graffinity Pharmaceutical Design GmbH · DE

Inventors

• Stefan Dickopf · Heidelberg, DE
• Kristina Schmidt · Heidelberg, DE
• Dirk Vetter · Heidelberg, DE
• Klaus Burkert · Heidelberg, DE

Key dates

• Filing date: Feb 21, 2001
• Grant date: Jun 22, 2004
• Expiry date: Jul 26, 2022

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N21/553
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention relates to an SPR sensor array comprising a plurality of SPR sensor surface areas (120) arranged on a substrate (10, 20) in a two-dimensional matrix located in a plane to which the SPR sensor surface areas (120) are parallel and whereby radiation capable of exciting surface plasmons in the SPR sensor surface areas (120) under specific physical conditions can be guided through the substrate (10, 20) to be reflected from the SPR sensor surface areas, as well as separating means (110) for separating each SPR sensor surface area (120) from its neighboring SPR sensor surface area (120), wherein the separating means (110) and SPR sensor surface areas (120) are provided such that at least outside of surface plasmon resonance occurring in the SPR sensor surface areas (120) the radiation (40) guided through the substrate (10, 20) is reflected in the region of the separating means to a different degree than in the region of the SPR sensor surface areas (120) to create a contrast between the separating means (110) and the SPR sensor surface areas (120) at least outside of surface plasmon resonance occurring in the SPR sensor surface areas (120) in the radiation reflected by the …