Composition and methods for affecting metallocorrinoid uptake
US6752986B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 24, 2001 |
| Grant date | Jun 22, 2004 |
| Priority date | — |
| Expiry date | Jan 19, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/215
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compositions and methods for affecting metallocorrinoid uptake. The compositions and methods of the present invention are particularly useful in enhancing the uptake or availability of biologically active metallocorrinoids (e.g. cobalamin and its analogs). The present invention is particularly useful in the treatment or prevention of conditions that result from low expression or activity of proteins involved in the processing of metallocorrinoids, as well as in conditions which would benefit from enhanced uptake or availability of cobalamin or its biologically active analogs of cobalamin (e.g. cobalamin drug conjugates).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.