Process for preparing non-hygroscopic sodium valproate composition

US6752997B2 · kind B2 · utility

Assignee

• Taro Pharmaceuticals U.S.A., Inc. · US

Inventors

• Mohammed Safadi · Nazareth, IL
• Maya Barder · Haifa, IL
• Yechiel Golander · Herzliya, IL
• Avraham Yacobi · Englewood, US
• Daniel Moros · Larchmont, US
• Barrie Levitt · Mamaroneck, US
• Michael Friedman · Jerusalem, IL

Key dates

• Filing date: Jan 24, 2002
• Grant date: Jun 22, 2004
• Expiry date: Jan 24, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/2059
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention is directed to non-hygroscopic oral pharmaceutical compositions of a salt of valproic acid, and processes for preparing the compositions. The non-hygroscopic pharmaceutical compositions are prepared by blending a hygroscopic salt of valproic acid, carbomer, and a non-hygroscopic additive.