Chiral fluoroquinolone arginine salt forms

US6753333B2 · kind B2 · utility

Assignee

• Wockhardt Limited · IN

Inventors

• Noel De Souza · Mumbai, IN
• Shivkumar Agarwal · Aurangabad, IN
• Mahesh Vithalbhai Patel · Aurangabad, IN
• Satish Bhawsar · Aurangabad, IN
• Rupinder K. Beri · Aurangabad, IN
• Ravindra Dattatraya Yeole · Aurangabad, IN
• Nitin Shetty · Kalyan-Dombivli, IN

Key dates

• Filing date: Nov 22, 2002
• Grant date: Jun 22, 2004
• Expiry date: Nov 22, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/07
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to the new arginine salt forms of S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, a process for their preparation and pharmaceutical formulations which comprise those arginine salt forms as the active ingredient for its use in treating antimicrobial infections.