Preparation of sodium-hydrogen exchanger type-1 inhibitors
US6753334B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Nov 27, 2001 |
| Grant date | Jun 22, 2004 |
| Priority date | — |
| Expiry date | Nov 27, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D231/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to methods of preparing sodium-hydrogen exchanger type 1 (NHE-1) inhibitors of formula I′intermediates of the NHE-1 inhibitors and a new almost colorless form of the NHE-1 inhibitor N-(5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carbonyl)-guanidine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.