Enterococcus antigens and vaccines
US6756361B1 · kind B1 · utility
14Cited by
26References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 14, 1997 |
| Grant date | Jun 29, 2004 |
| Priority date | — |
| Expiry date | Nov 22, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S424/831
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A majority of E. faecalis and E. faecium clinical isolates fall into two groups and three groups, respectively. Distinct antigens are associate with each of the five groups. The Enterococcus antigens are readily obtained from strains of E. faecalis and E. faecium, and can elicit production of protective antibodies. Accordingly, the antigens are useful for vaccines which protect against infection by clinically significant (pathogenic) Enterococcus isolates. The antigens and antibodies generated to the antigens are also useful in diagnostic assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.