Patent · US Expired

Nucleoside derivatives with photo-unstable protective groups

US6756492B1 · kind B1 · utility

3Cited by

4References

8Claims

0Family size

Assignee

DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS · DE

Inventors

Markus Beier · Heidelberg, DE
Jörg Honeisel · Wiesloch, DE

Key dates

Filing date	Feb 21, 2002
Grant date	Jun 29, 2004
Priority date	—
Expiry date	Feb 21, 2022

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to nucleoside derivatives having photolabile protective groups of general formula (I) in whichR1=H, NO2, CN, OCH3, halogen, an alkyl, alkoxy or alkoxyalkyl residue having 1 to 4 C atoms or an optionally substituted aryl residue or an aliphatic acyl residue having 2 to 5 atoms,R2=H, NO2, CN, OCH3, halogen, an alkyl, alkoxy or alkoxyalkyl residue having 1 to 4 C atoms or an optionally substituted aryl residue or an aliphatic acyl residue having 2 to 5 atoms,R3=H, halogen, NO2, CN, OCH3, an alkyl, alkoxy or alkoxyalkyl residue having 1 to 4 C atoms or an optionally substituted aryl residue or aliphatic acyl residue having 2 to 5 C atoms,R4=H, halogen, NO2, CN, OCH3, an alkyl, alkoxy, or alkoxyalkyl residue having 1 to 4 C atoms or an optionally substituted aryl residue or aliphatic acyl residue having 2 to 5 atoms,R5=H, dimethoxytrityl or a protective group common in the chemistry of nucleotides or a functional group common for the production of oligonucleotides,R6=H, OH, halogen, or &PSgr;R8, wherein &PSgr;=O or S and R8=alkyl or alkoxyalkyl having 1 to 4 C atoms or an optionally substituted aryl residue or an aliphatic acyl residue having 2 to 5 atoms a…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.