Increased drug-loading and reduced stress drug delivery device
US6758859B1 · kind B1 · utility
Inventors
Key dates
| Filing date | Oct 30, 2000 |
| Grant date | Jul 6, 2004 |
| Priority date | — |
| Expiry date | Dec 14, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2250/0068
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An implantable prosthesis, for example a stent, is provided having one or more elements that form the body structure of the prosthesis. The elements have a width that is variable from a nominal or conventional width to an increased width. Depots are formed in the elements and are generally located at the increased width portions of the elements. The diameter of the depots is based on a percentage of the width of the element. As such, the depots have increased drug-loading capabilities. Substances such as therapeutic substances, polymeric materials, polymeric materials containing therapeutic substances, radioactive isotopes, and radiopaque materials can be deposited into the depots. Further, the variable width of the elements ensures that sufficient material surrounds each depot so as not to compromise the structural integrity of the prosthesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.