Detection of human hepatitis B virus surface antigen mutants by specific amplification and its application on gene chip
US6759193B2 · kind B2 · utility
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36Claims
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Key dates
| Filing date | Jul 28, 1999 |
| Grant date | Jul 6, 2004 |
| Priority date | — |
| Expiry date | Jul 28, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6837
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel DNA probe sequences for detection, by polymerase chain reaction, of human hepatitis B virus surface antigen mutant 145 (Glycine to Arginine) from serum samples. As a direct application, these specific DNA probes are immobilized on solid glass supports (gene chip) for detection of human hepatitis B virus surface antigen mutant 145 (Glycine to Arginine) by fluorescence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.