Enzymes for the detection of specific nucleic acid sequences
US6759226B1 · kind B1 · utility
29Cited by
17References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 24, 2000 |
| Grant date | Jul 6, 2004 |
| Priority date | — |
| Expiry date | May 24, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to novel enzymes designed for direct detection, characterization and quantitation of nucleic acids, particularly RNA. The present invention provides enzymes that recognize specific nucleic acid cleavage structures formed on a target RNA sequence and that cleave the nucleic acid cleavage structure in a site-specific manner to produce non-target cleavage products. The present invention provides enzymes having an improved ability to specifically cleave a DNA member of a complex comprising DNA and RNA nucleic acid strands.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.