Metalloporphyrins and their uses as radiosensitizers for radiation therapy
US6759403B2 · kind B2 · utility
6Cited by
10References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 5, 2002 |
| Grant date | Jul 6, 2004 |
| Priority date | — |
| Expiry date | Apr 5, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention covers radiosensitizers containing as an active ingredient halogenated derivatives of boronated porphyrins containing multiple carborane cages having the structure which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron—capture therapy and photodynamic therapy. The present invention also covers methods for using these radiosensitizers in tumor imaging and cancer treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.