Branched peptide linkers
US6759509B1 · kind B1 · utility
135Cited by
16References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 31, 1997 |
| Grant date | Jul 6, 2004 |
| Priority date | — |
| Expiry date | Oct 31, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Conjugates containing a targeting ligand, such as an antibody, a therapeutically active drug and a branched peptide linker. The branched peptide linker contains two or more amino acid moieties that provide an enzyme cleavage site. The number of drugs capable of being bonded to the branched linkers varies by a factor of two for each generation of branching.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.