Compound used as an amino-protecting group, process for preparing the same, and synthetic method of a peptide using the same
US6759511B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Oct 31, 2002 |
| Grant date | Jul 6, 2004 |
| Priority date | — |
| Expiry date | Dec 14, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a carbonic acid ester compound of the following formula (1): in which X, Y, and Ar are defined in the specification, which can be easily combined with the amino group of an amino acid or removed therefrom under mild conditions, whereby the amino group can be effectively protected during peptide syntheses, process for preparing the same, and use of the same. Since the amino acid derivatives thus protected have high thermal and chemical stabilities and good solubility for organic solvents, peptides can be synthesized at a low cost with a high yield.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.