Patent · US Expired

Single-chain multiple antigen-binding molecule, its preparation and use

US6759518B1 · kind B1 · utility

63Cited by

4References

19Claims

0Family size

Assignee

Vectron Therapeutics AG · DE

Inventors

Roland Kontermann · Jeffery Road, DE
Hans-Harald Sedlacek · Marburg, DE
Rolf Mueller · Ingolstadt, DE

Key dates

Filing date	Apr 9, 1999
Grant date	Jul 6, 2004
Priority date	—
Expiry date	Apr 9, 2019

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a single-chain, multiple antigen-binding molecule with diverse variable domains of a heavy and of a light chain of an immunoglobulin, which are connected in the form of a VH-VL construct, which are in turn connected together via a peptide, and to the preparation and use thereof as pharmaceutical or diagnostic aid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.